Skip to content

End-tidal carbon dioxide levels in patients with post-concussion syndrome during neurocognitive and physical tasks compared to a normative control group

Brain Inj. 2018 Sep;

[Epub ahead of print](1-Aug):1-10.

Siedlecki, P., Sanzo, P., Zerpa, C. and Newhouse, I..

FEE $

Wouldn’t it be nice to earn CME Credits for the research work you’re already doing?

Abstract:

PRIMARY OBJECTIVE: Recent findings suggest breathing may negatively affect performance after concussion. The aim of the study was to examine group differences between individuals with and without post-concussion syndrome (PCS) in end-tidal carbon dioxide (ETCO2) and respiratory rate (RR) during neurocognitive and physical tasks. HYPOTHESIS: Individuals in the PCS group will have elevated ETCO2 and lower RR compared to the control group. METHODS: A quasi-experimental study was used in which a capnography unit collected ETCO2 and RR breathing data from 22 participants (control = 17; PCS = 5) during rest, the completion of the Immediate Post-Concussion Assessment and Cognitive Test (ImPACT) battery and while slow and fast walking. Four repeated measures mixed factorial ANOVAs, with an alpha level set at p </= 0.05, were used to examine group and task differences. RESULTS: Both groups displayed similar breathing responses to cognitive and physical stress; however, PCS participants had significantly elevated ETCO2 throughout the study (during rest, the ImPACT and while walking) compared to the control. Conversely, no significant group differences were found in RR. CONCLUSION: Cerebral physiological alterations and deficits in the autonomic nervous system may cause abnormal ETCO2 in individuals after concussion. Future research evaluating breathing patterns in PCS may be warranted.

Links to full article: